Anarchy Reigns

The player controls one of numerous fighters, each using their own unique moveset to defeat their opponents. The player can also fight other players online in Multiplayer Mode. The game includes separate story campaigns for two characters: the "Black Side" campaign featuring returning MadWorld protagonist Jack Cayman and the "White Side" campaign featuring new character Leonhardt "Leo" Victorion. The stories occur in parallel in an open world, intersecting at various points, before converging in a final "Red Side" campaign unlocked after clearing both.

The game features seventeen playable characters and one additional DLC character. Returning from MadWorld is protagonist Jack Cayman, an agent of the Chaser Guild, who is tasked to find escaped fugitive Maximillian Caxton. Competing with Jack to find and capture Max first is Max's former team, the Strike One unit, made up of villainous leader Nikolai Dmitri Bulygin, female agent Sasha Ivanoff, and reluctant agent Leonhardt "Leo" Victorion. Along with Jack, several other MadWorld characters appear, including former final boss the Blacker Baron and his assistant Mathilda, cyborg bull Big Bull Crocker, and Crimson Dragons clan member Rin Rin.

Other playable characters include Rin Rin's sisters Fei Rin and Ai Rin, cyborg bounty-hunting partners Durga and Garuda, cybernetic ninja Zero, junk seller Edgar Oinkie, mutant hunter Douglas Williamsburg, and mass-produced combat mech the Gargoyle. The titular hero of PlatinumGames' Bayonetta is also playable via downloadable content.

The game received "mixed or average" reviews on both platforms according to the review aggregation website Metacritic. Richard Mitchell of Joystiq praised the Xbox 360 version's good vocal performances, well-designed characters and well-performed story, but criticized the limited combat, irritating matchmaking problem and lack of competitiveness in the multiplayer modes. Mark Walton of GameSpot praised the same console version's satisfying combat, but criticized the story, repetitive single-player missions, lack of fluidity in combat, disappointing visuals, repeated textures and environment, as well as generic character design as he described most characters as "muscular video game guys, or overtly sexualised females". Chris Carter of Destructoid praised the soundtrack as well as the huge variety of playable characters, allowing players to play in every playstyle possible.

However, he criticized the lack of split-screen capabilities. He also stated that the combat would be nuanced, and a bit complicated for starters, but brawler fans should find everything they're looking for with Anarchy Reigns. Mitch Dyer of IGN praised the concept of the multiplayer, but criticized the frustrating mission design which leads to repetition, disappointing and weak story, inconsistent tone, empty world, as well as numerous technical issues, such as framerate problems and fuzzy visuals. Rich Stanton of Eurogamer praised the satisfying gameplay and the multiplayer, but criticized the camera and the fighting styles that despite being various share the same visual foundations.