Resident Evil Portable

The early Resident Evil games focused on the Umbrella Corporation, an international pharmaceutical company that secretly develops mutagenic viruses to further their "bio-organic weapons" (BOW) research. The company's viruses can transform humans into mindless zombies while also mutating plants and animals into horrifying monstrosities. The Umbrella Corporation uses its vast resources to effectively control Raccoon City, a fictional midwestern American city. In the original Resident Evil, members of an elite police task force, Special Tactics and Rescue Service (STARS), are lured to a derelict mansion on the outskirts of Raccoon City.

The STARS team is mostly decimated by zombies and other BOWs, leaving only a handful of survivors, including Chris Redfield, Jill Valentine, and Albert Wesker. Chris and Jill explore the zombie-infested mansion and uncover a secret underground Umbrella research facility. Wesker reveals himself to be a double agent for Umbrella and betrays his comrades. However, Wesker is seemingly murdered by a Tyrant, a special BOW that is the culmination of the Umbrella Corporation's research.

The development of the first Resident Evil, released as Biohazard in Japan, began in 1993 when Capcom's Tokuro Fujiwara told Shinji Mikami and other co-workers to create a game using elements from Fujiwara's 1989 game Sweet Home on the Family Computer (Famicom) in Japan. When in late 1994 marketing executives were setting up to release Biohazard in the United States, it was pointed out that securing the rights to the name Biohazard would be very difficult as a DOS game had been registered under that name, as well as a New York hardcore punk band called Biohazard. A contest was held among company personnel to choose a new name; this competition turned up Resident Evil, the name under which it was released in the west. Resident Evil made its debut on the PlayStation in 1996 and was ported to the Sega Saturn.

The first entry in the series was the first game to be dubbed a "survival horror", a term coined for the new genre it initiated, and its critical and commercial success led to the production of two sequels, Resident Evil 2 in 1998 and Resident Evil 3: Nemesis in 1999, both for the PlayStation. A port of Resident Evil 2 was released for the Nintendo 64. In addition, ports of all three were released for Windows. The next big game in the series, Resident Evil – Code: Veronica, was developed for the Dreamcast and released in 2000, followed by ports of Resident Evil 2 and Resident Evil 3: Nemesis.

Most of the games in the prominent Resident Evil series have been released to positive reviews. Some of the games, most notably Resident Evil, Resident Evil 2 and Resident Evil 4, have been bestowed with multiple Game of the Year honors and often placed on lists of the best video games ever made.

In 1999, Next Generation listed the Resident Evil series as number 13 on their "Top 50 Games of All Time", commenting that, "Flawless graphics, excellent music, and a top-notch storyline all combined to make a game of unparalleled atmosphere and suspense." In 2012, Complex ranked Resident Evil at number 22 on the list of the best video game franchises. That same year, G4tv called it "one of the most successful series in gaming history."