Q.U.B.E. 2

The player's character, after waking up from some incident, finds himself with a pair of gloves that can interact with specific blocks that are in the walls, floors, and ceilings of the various rooms as he progresses. The function of the blocks are distinguished by colour: red blocks can be extended or retracted; yellow blocks, always in groups of three, can be used to make stair-like structures; blue blocks can be retracted to act like a springboard to whatever touches them; purple blocks provide means to rotate sections of walls of a room; and green blocks provide a sphere or cube, which the player will need to manipulate. In the early stages, the player's goal is to use a combination of these blocks to get themselves to an exit point, allowing them to move to the next chamber.

As the player progresses deeper into the unknown complex, new puzzle aspects are introduced. In one stage, the bulk of the chambers are dark except for specific coloured blocks, requiring the player to remember the location of other blocks as they manipulate them. Another section features light-oriented puzzles, with the player using cubes and other features to orient the light beam in the correct fashion.

E. represents the final student project of Daniel Da Rocha, Jonathan Savery and Dave Hall, at Newport University. Upon graduation, the three had received strong feedback for their game, and founded their own company, Toxic Games, to continue its development. During this initial period of development, the team had considered the difficulty of obtaining publishing deals given their inexperience in the field, but instead happened upon funding provided by the Indie Fund, based on the potential of their game, allowing them to work at a more relaxed pace while retaining the intellectual property for themselves.

E. represents the first game funded through the Indie Fund to be released. Aaron Isaksen of the Indie Fund noted that they were drawn to the project while it was still a student project, believing the first-person puzzle game offered new concepts and ideas while providing a clean and simple interface without any time pressure or pin-point accuracy for the player. E's development starting in August 2010.

Q.U.B.E. was one of the twelve finalists, but did not win, for the 2011 Indie Game Challenge sponsored by the Academy of Interactive Arts & Sciences.

The game received an aggregated score of 69/100 on Metacritic, indicating mixed or average reviews. Reviewers noted that the game was immediately comparable to the two Portal games, providing puzzles within a sterile environment. The game was praised for building on similar puzzle mechanics while introducing its own ideas. Puzzles involving magnetism, however, were found to be rather tedious compared to the other puzzle elements.